This paper looked at outcomes of patients treated with intramuscular and sublingual ketamine.
Patients were given in office or at home use of ketamine for treatment of various mental health issues including childhood trauma. They found significant improvements for patients with many diagnoses with only a small subset experienced adverse effects such as nausea and vomiting. In addition, they found that ketamine did not produce any physical dependence. They were also able to conclude that patients with more severe symptoms including suicidal ideational tended to show more significant benefit with administration of ketamine.
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